Evolutionary Divergence of the C-terminal Domain of Complexin Accounts for Functional Disparities between Vertebrate and Invertebrate Complexins

Complexin is a critical presynaptic protein that regulates both spontaneous and calcium-triggered neurotransmitter release in all synapses. Although the SNARE-binding central helix of complexin is highly conserved and required for all known complexin functions, the remainder of the protein has profo...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Wragg, Rachel T., Parisotto, Daniel A., Li, Zhenlong, Terakawa, Mayu S., Snead, David, Basu, Ishani, Weinstein, Harel, Eliezer, David, Dittman, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445133/
https://ncbi.nlm.nih.gov/pubmed/28603484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00146
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