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Membrane curvature sensing by the C-terminal domain of complexin

Complexin functions at presynaptic nerve terminals to inhibit spontaneous SNARE-mediated synaptic vesicle exocytosis, while enhancing stimulated neurotransmitter release. The C-terminal domain (CTD) of complexin is essential for its inhibitory function and has been implicated in localizing complexin...

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Detalhes bibliográficos
Main Authors: Snead, David, Wragg, Rachel T., Dittman, Jeremy S., Eliezer, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180495/
https://ncbi.nlm.nih.gov/pubmed/25229806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5955
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