C-terminal domain of mammalian complexin-1 localizes to highly curved membranes

In presynaptic nerve terminals, complexin regulates spontaneous “mini” neurotransmitter release and activates Ca(2+)-triggered synchronized neurotransmitter release. We studied the role of the C-terminal domain of mammalian complexin in these processes using single-particle optical imaging and elect...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gong, Jihong, Lai, Ying, Li, Xiaohong, Wang, Mengxian, Leitz, Jeremy, Hu, Yachong, Zhang, Yunxiang, Choi, Ucheor B., Cipriano, Daniel, Pfuetzner, Richard A., Südhof, Thomas C., Yang, Xiaofei, Brunger, Axel T., Diao, Jiajie
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127347/
https://ncbi.nlm.nih.gov/pubmed/27821736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609917113
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