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Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex
Complexin regulates spontaneous and activates Ca(2+)-triggered neurotransmitter release, yet the molecular mechanisms are still unclear. Here we performed single molecule fluorescence resonance energy transfer experiments and uncovered two conformations of complexin-1 bound to the ternary SNARE comp...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4927292/ https://ncbi.nlm.nih.gov/pubmed/27253060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16886 |
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