NSF-mediated disassembly of on- and off-pathway SNARE complexes and inhibition by complexin

SNARE complex disassembly by the ATPase NSF is essential for neurotransmitter release and other membrane trafficking processes. We developed a single-molecule FRET assay to monitor repeated rounds of NSF-mediated disassembly and reassembly of individual SNARE complexes. For ternary neuronal SNARE co...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Choi, Ucheor B, Zhao, Minglei, White, K Ian, Pfuetzner, Richard A, Esquivies, Luis, Zhou, Qiangjun, Brunger, Axel T
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Microbiology and Infectious Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130971/
https://ncbi.nlm.nih.gov/pubmed/29985126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36497
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