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The accessory helix of complexin functions by stabilizing central helix secondary structure

The presynaptic protein complexin (CPX) is a critical regulator of synaptic vesicle fusion, but the mechanisms underlying its regulatory effects are not well understood. Its highly conserved central helix (CH) directly binds the ternary SNARE complex and is required for all known CPX functions. The...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Radoff, Daniel T, Dong, Yongming, Snead, David, Bai, Jihong, Eliezer, David, Dittman, Jeremy S
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270070/
https://ncbi.nlm.nih.gov/pubmed/25383924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04553
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