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The accessory helix of complexin functions by stabilizing central helix secondary structure
The presynaptic protein complexin (CPX) is a critical regulator of synaptic vesicle fusion, but the mechanisms underlying its regulatory effects are not well understood. Its highly conserved central helix (CH) directly binds the ternary SNARE complex and is required for all known CPX functions. The...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270070/ https://ncbi.nlm.nih.gov/pubmed/25383924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04553 |
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