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Complexin Binding to Membranes and Acceptor t-SNAREs Explains Its Clamping Effect on Fusion
Complexin-1 is a SNARE effector protein that decreases spontaneous neurotransmitter release and enhances evoked release. Complexin binds to the fully assembled four-helical neuronal SNARE core complex as revealed in competing molecular models derived from x-ray crystallography. Presently, it is uncl...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607037/ https://ncbi.nlm.nih.gov/pubmed/28456331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.04.002 |
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