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Dantrolene is neuroprotective in Huntington's disease transgenic mouse model
BACKGROUND: Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine expansion in the Huntingtin protein which results in the selective degeneration of striatal medium spiny neurons (MSNs). Our group has previously demonstrated that calcium (Ca(2+)) signal...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235068/ https://ncbi.nlm.nih.gov/pubmed/22118545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-81 |
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