Ataxic Symptoms in Huntington’s Disease Transgenic Mouse Model Are Alleviated by Chlorzoxazone

Huntington’s disease (HD) is a hereditary neurodegenerative disease caused by a polyglutamine expansion in the huntingtin protein, Striatum atrophy in HD leads to a progressive disturbance of psychiatric, motor, and cognitive function. Recent studies of HD patients revealed that the degeneration of...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Egorova, Polina A., Gavrilova, Aleksandra V., Bezprozvanny, Ilya B.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147686/
https://ncbi.nlm.nih.gov/pubmed/32317916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00279
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