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In vivo analysis of the climbing fiber – Purkinje cell circuit in SCA2-58Q transgenic mouse model

Cerebellar Purkinje cells (PCs) and cerebellar pathways are primarily affected in many autosomal dominant cerebellar ataxias. PCs generate complex spikes (CS) in vivo when activated by climbing fiber (CF) which rise from the inferior olive. In this study we investigated the functional state of the C...

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Detalles Bibliográficos
Publicado en:Cerebellum
Main Authors: Egorova, Polina A., Gavrilova, Alexandra V., Bezprozvanny, Ilya B.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281806/
https://ncbi.nlm.nih.gov/pubmed/29876801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-018-0951-4
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