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An Automated and Quantitative Method to Evaluate Progression of Striatal Pathology in Huntington’s Disease Transgenic Mice
Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine expansion in the Huntingtin protein which results in the selective degeneration of striatal medium spiny neurons (MSN). A number of genetic mouse models have been developed to model HD phenotype. Most of...
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| Publicado no: | J Huntingtons Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317287/ https://ncbi.nlm.nih.gov/pubmed/25575955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-140128 |
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