Neuroprotective Effects of Creatine in a Transgenic Mouse Model of Huntington's Disease

Huntington's disease (HD) is a progressive neurodegenerative illness for which there is no effective therapy. We examined whether creatine, which may exert neuroprotective effects by increasing phosphocreatine levels or by stabilizing the mitochondrial permeability transition, has beneficial ef...

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Pubblicato in:J Neurosci
Autori principali: Ferrante, Robert J., Andreassen, Ole A., Jenkins, Bruce G., Dedeoglu, Alpaslan, Kuemmerle, Stefan, Kubilus, James K., Kaddurah-Daouk, Rima, Hersch, Steven M., Beal, M. Flint
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772461/
https://ncbi.nlm.nih.gov/pubmed/10844007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-12-04389.2000
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