Neuroprotective Effects of Creatine in a Transgenic Mouse Model of Huntington's Disease

Huntington's disease (HD) is a progressive neurodegenerative illness for which there is no effective therapy. We examined whether creatine, which may exert neuroprotective effects by increasing phosphocreatine levels or by stabilizing the mitochondrial permeability transition, has beneficial ef...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Ferrante, Robert J., Andreassen, Ole A., Jenkins, Bruce G., Dedeoglu, Alpaslan, Kuemmerle, Stefan, Kubilus, James K., Kaddurah-Daouk, Rima, Hersch, Steven M., Beal, M. Flint
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772461/
https://ncbi.nlm.nih.gov/pubmed/10844007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-12-04389.2000
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