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Neuroprotective Effects of Creatine and Cyclocreatine in Animal Models of Huntington’s Disease

The gene defect in Huntington’s disease (HD) may result in an impairment of energy metabolism. Malonate and 3-nitropropionic acid (3-NP) are inhibitors of succinate dehydrogenase that produce energy depletion and lesions that closely resemble those of HD. Oral supplementation with creatine or cycloc...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Matthews, Russell T., Yang, Lichuan, Jenkins, Bruce G., Ferrante, Robert J., Rosen, Bruce R., Kaddurah-Daouk, Rima, Beal, M. Flint
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793381/
https://ncbi.nlm.nih.gov/pubmed/9412496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-01-00156.1998
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