Neuroprotective Effects of Creatine in a Transgenic Mouse Model of Huntington's Disease

Huntington's disease (HD) is a progressive neurodegenerative illness for which there is no effective therapy. We examined whether creatine, which may exert neuroprotective effects by increasing phosphocreatine levels or by stabilizing the mitochondrial permeability transition, has beneficial ef...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ferrante, Robert J., Andreassen, Ole A., Jenkins, Bruce G., Dedeoglu, Alpaslan, Kuemmerle, Stefan, Kubilus, James K., Kaddurah-Daouk, Rima, Hersch, Steven M., Beal, M. Flint
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772461/
https://ncbi.nlm.nih.gov/pubmed/10844007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-12-04389.2000
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