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Tumor Suppressor Protein Pdcd4 Inhibits Translation of p53 mRNA

The tumor suppressor protein Pdcd4 is thought to suppress translation of mRNAs containing structured 5′-UTRs by interacting with translation initiation factor eIF4A and inhibiting its helicase activity. However, natural target mRNAs regulated by Pdcd4 so far are mostly unknown. Here, we identified p...

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Bibliografski detalji
Glavni autori: Wedeken, Lena, Singh, Priyanka, Klempnauer, Karl-Heinz
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234825/
https://ncbi.nlm.nih.gov/pubmed/22033922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269456
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