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Association of Tumor Suppressor Protein Pdcd4 With Ribosomes Is Mediated by Protein-Protein and Protein-RNA Interactions

The Pdcd4 (programmed cell death gene 4) gene has been implicated as a novel tumor suppressor gene in the development of several types of human cancer. The Pdcd4 protein is believed to act as a translation suppressor of mRNAs containing structured 5′ UTRs. Pdcd4 contains 2 copies of so-called MA3 do...

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Detalhes bibliográficos
Main Authors: Wedeken, Lena, Ohnheiser, Johanna, Hirschi, Benjamin, Wethkamp, Nils, Klempnauer, Karl-Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092196/
https://ncbi.nlm.nih.gov/pubmed/21779451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910364227
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