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Tumor Suppressor Protein Pdcd4 Inhibits Translation of p53 mRNA
The tumor suppressor protein Pdcd4 is thought to suppress translation of mRNAs containing structured 5′-UTRs by interacting with translation initiation factor eIF4A and inhibiting its helicase activity. However, natural target mRNAs regulated by Pdcd4 so far are mostly unknown. Here, we identified p...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234825/ https://ncbi.nlm.nih.gov/pubmed/22033922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269456 |
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