Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator

The antitumor activities of the novel adenosine monophosphate-activated protein kinase (AMPK) activator, OSU-53, were assessed in in vitro and in vivo models of triple-negative breast cancer. OSU-53 directly stimulated recombinant AMPK kinase activity (EC(50), 0.3 μm) and inhibited the viability and...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Lee, Kuen-Haur, Hsu, En-Chi, Guh, Jih-Hwa, Yang, Hsiao-Ching, Wang, Dasheng, Kulp, Samuel K., Shapiro, Charles L., Chen, Ching-Shih
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
Metabolism
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234749/
https://ncbi.nlm.nih.gov/pubmed/21917926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264598
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍