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Targeting myeloid-derived suppressor cells using a novel adenosine monophosphate-activated protein kinase (AMPK) activator

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of early myeloid cells that accumulate in the blood and tumors of patients with cancer. MDSC play a critical role during tumor evasion and promote immune suppression through variety of mechanisms, such as the generation of reacti...

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Vydáno v:Oncoimmunology
Hlavní autoři: Trikha, Prashant, Plews, Robert L., Stiff, Andrew, Gautam, Shalini, Hsu, Vincent, Abood, David, Wesolowski, Robert, Landi, Ian, Mo, Xiaokui, Phay, John, Chen, Ching-Shih, Byrd, John, Caligiuri, Michael, Tridandapani, Susheela, Carson, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048767/
https://ncbi.nlm.nih.gov/pubmed/27757311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1214787
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