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Small molecule adenosine 5′-monophosphate activated protein kinase (AMPK) modulators and human diseases

Adenosine 5′-monophosphate activated protein kinase (AMPK) is a master sensor of cellular energy status that plays a key role in the regulation of whole-body energy homeostasis. AMPK is a serine/threonine kinase that is activated by upstream kinases LKB1, CaMKKβ and Tak1 among others. AMPK exists as...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Rana, Sandeep, Blowers, Elizabeth C., Natarajan, Amarnath
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864506/
https://ncbi.nlm.nih.gov/pubmed/25122135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401994c
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