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Molecular Coupling in the Human ether-a-go-go-related gene-1 (hERG1) K(+) Channel Inactivation Pathway

Emerging evidence suggests that K(+) channel inactivation involves coupling between residues in adjacent regions of the channel. Human ether-a-go-go-related gene-1 (hERG1) K(+) channels undergo a fast inactivation gating process that is crucial for maintaining electrical stability in the heart. The...

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Main Authors: Ferrer, Tania, Cordero-Morales, Julio F., Arias, Marcelo, Ficker, Eckhard, Medovoy, David, Perozo, Eduardo, Tristani-Firouzi, Martin
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234734/
https://ncbi.nlm.nih.gov/pubmed/21908602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.292060
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