Oncogenic ras-induced Down-regulation of Pro-apoptotic Protease Caspase-2 Is Required for Malignant Transformation of Intestinal Epithelial Cells

Resistance of carcinoma cells to anoikis, apoptosis that is normally induced by loss of cell-to-extracellular matrix adhesion, is thought to be essential for the ability of these cells to form primary tumors, invade adjacent tissues, and metastasize to distant organs. Current knowledge about the mec...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yoo, Byong Hoon, Wang, Yanfei, Erdogan, Mete, Sasazuki, Takehiko, Shirasawa, Senji, Corcos, Laurent, Sabapathy, Kanaga, Rosen, Kirill V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234714/
https://ncbi.nlm.nih.gov/pubmed/21903589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290692
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