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Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes

Rett syndrome (RTT) is a disorder that affects patients' ability to communicate, move and behave. RTT patients are characterized by impaired language, stereotypic behaviors, frequent seizures, ataxia and sleep disturbances, with the onset of symptoms occurring after a period of seemingly normal...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kerr, Bredford, Soto C, Jessica, Saez, Mauricio, Abrams, Alexander, Walz, Katherina, Young, Juan I
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234513/
https://ncbi.nlm.nih.gov/pubmed/21829232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.145
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