Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes

Rett syndrome (RTT) is a disorder that affects patients' ability to communicate, move and behave. RTT patients are characterized by impaired language, stereotypic behaviors, frequent seizures, ataxia and sleep disturbances, with the onset of symptoms occurring after a period of seemingly normal...

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Bibliographic Details
Main Authors: Kerr, Bredford, Soto C, Jessica, Saez, Mauricio, Abrams, Alexander, Walz, Katherina, Young, Juan I
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234513/
https://ncbi.nlm.nih.gov/pubmed/21829232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.145
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