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Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes

Rett syndrome (RTT) is a disorder that affects patients' ability to communicate, move and behave. RTT patients are characterized by impaired language, stereotypic behaviors, frequent seizures, ataxia and sleep disturbances, with the onset of symptoms occurring after a period of seemingly normal...

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Detalhes bibliográficos
Main Authors: Kerr, Bredford, Soto C, Jessica, Saez, Mauricio, Abrams, Alexander, Walz, Katherina, Young, Juan I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234513/
https://ncbi.nlm.nih.gov/pubmed/21829232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.145
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