Načítá se...

Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice

Mutations in MECP2 are the cause of Rett syndrome (RTT) in humans, a neurodevelopmental disorder that affects mainly girls. MeCP2 is a protein that binds CpG dinucleotides and is thought to act as a global transcriptional repressor. It is highly expressed in neurons, but not in glia, of the postnata...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Luikenhuis, Sandra, Giacometti, Emanuela, Beard, Caroline F., Jaenisch, Rudolf
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC395918/
https://ncbi.nlm.nih.gov/pubmed/15069197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401626101
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!