Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

Rett Syndrome (RTT) is a severe form of X-linked mental retardation caused by mutations in the gene coding for methyl CpG-binding protein 2 (MECP2). Mice deficient in MeCP2 have a range of physiological and neurological abnormalities that mimic the human syndrome. Here we show that systemic treatmen...

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Detaylı Bibliyografya
Asıl Yazarlar: Tropea, Daniela, Giacometti, Emanuela, Wilson, Nathan R., Beard, Caroline, McCurry, Cortina, Fu, Dong Dong, Flannery, Ruth, Jaenisch, Rudolf, Sur, Mriganka
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644158/
https://ncbi.nlm.nih.gov/pubmed/19208815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812394106
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