Role of NADPH Oxidase versus Neutrophil Proteases in Antimicrobial Host Defense

NADPH oxidase is a crucial enzyme in mediating antimicrobial host defense and in regulating inflammation. Patients with chronic granulomatous disease, an inherited disorder of NADPH oxidase in which phagocytes are defective in generation of reactive oxidant intermediates (ROIs), suffer from life-thr...

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Библиографические подробности
Главные авторы: Vethanayagam, R. Robert, Almyroudis, Nikolaos G., Grimm, Melissa J., Lewandowski, David C., Pham, Christine T. N., Blackwell, Timothy S., Petraitiene, Ruta, Petraitis, Vidmantas, Walsh, Thomas J., Urban, Constantin F., Segal, Brahm H.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233573/
https://ncbi.nlm.nih.gov/pubmed/22163282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028149
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