Role of NADPH Oxidase versus Neutrophil Proteases in Antimicrobial Host Defense

NADPH oxidase is a crucial enzyme in mediating antimicrobial host defense and in regulating inflammation. Patients with chronic granulomatous disease, an inherited disorder of NADPH oxidase in which phagocytes are defective in generation of reactive oxidant intermediates (ROIs), suffer from life-thr...

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Hlavní autoři: Vethanayagam, R. Robert, Almyroudis, Nikolaos G., Grimm, Melissa J., Lewandowski, David C., Pham, Christine T. N., Blackwell, Timothy S., Petraitiene, Ruta, Petraitis, Vidmantas, Walsh, Thomas J., Urban, Constantin F., Segal, Brahm H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233573/
https://ncbi.nlm.nih.gov/pubmed/22163282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028149
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