NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis

NADPH oxidase is a crucial enzyme in antimicrobial host defense and in regulating inflammation. Chronic granulomatous disease (CGD) is an inherited disorder of NADPH oxidase in which phagocytes are defective in generation of reactive oxidant intermediates. Aspergillus species are ubiquitous, filamen...

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Bibliographic Details
Main Authors: Röhm, Marc, Grimm, Melissa J., D'Auria, Anthony C., Almyroudis, Nikolaos G., Segal, Brahm H., Urban, Constantin F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993456/
https://ncbi.nlm.nih.gov/pubmed/24549323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00096-14
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