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NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis

NADPH oxidase is a crucial enzyme in antimicrobial host defense and in regulating inflammation. Chronic granulomatous disease (CGD) is an inherited disorder of NADPH oxidase in which phagocytes are defective in generation of reactive oxidant intermediates. Aspergillus species are ubiquitous, filamen...

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Detalhes bibliográficos
Main Authors: Röhm, Marc, Grimm, Melissa J., D'Auria, Anthony C., Almyroudis, Nikolaos G., Segal, Brahm H., Urban, Constantin F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993456/
https://ncbi.nlm.nih.gov/pubmed/24549323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00096-14
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