NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis

NADPH oxidase is a crucial enzyme in antimicrobial host defense and in regulating inflammation. Chronic granulomatous disease (CGD) is an inherited disorder of NADPH oxidase in which phagocytes are defective in generation of reactive oxidant intermediates. Aspergillus species are ubiquitous, filamen...

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Main Authors: Röhm, Marc, Grimm, Melissa J., D'Auria, Anthony C., Almyroudis, Nikolaos G., Segal, Brahm H., Urban, Constantin F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993456/
https://ncbi.nlm.nih.gov/pubmed/24549323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00096-14
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