Monocyte and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice

Chronic granulomatous disease, an inherited disorder of the NADPH oxidase in which phagocytes are defective in the generation of superoxide anion and downstream reactive oxidant species, is characterized by severe bacterial and fungal infections and excessive inflammation. Although NADPH oxidase iso...

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Detaylı Bibliyografya
Asıl Yazarlar: Grimm, Melissa J., Vethanayagam, R. Robert, Almyroudis, Nikolaos G., Dennis, Carly G., Khan, A. Nazmul H., D’Auria, Anthony, Singel, Kelly L., Davidson, Bruce A., Knight, Paul R., Blackwell, Timothy S., Hohl, Tobias M., Mansour, Michael K., Vyas, Jatin M., Röhm, Marc, Urban, Constantin F., Kelkka, Tiina, Holmdahl, Rikard, Segal, Brahm H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622122/
https://ncbi.nlm.nih.gov/pubmed/23509361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202800
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