Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen sensitivity of prostate cancer cells

We identified the molecular target by histone deacetylase (HDAC) inhibitors for exploring their potential prostate cancer (PCa) therapy. Upon HDAC inhibitors-treatment, LNCaP cell growth was suppressed, correlating with increased cellular prostatic acid phosphatase (cPAcP) expression, an authentic p...

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Main Authors: Chou, Yu-Wei, Chaturvedi, Nagendra K., Ouyang, Shougiang, Lin, Fen-Fen, Kaushik, Dharm, Wang, Jue, Kim, Isaac, Lin, Ming-Fong
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232184/
https://ncbi.nlm.nih.gov/pubmed/21862211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.07.015
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