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Epigenetic suppression of the antitumor cytotoxicity of NK cells by histone deacetylase inhibitor valproic acid

Natural killer (NK) cells play an essential role in the fight against tumor development. The therapeutic use of autologous NK cells has been exploited to treat human malignancies, yet only limited antitumor activity is observed in cancer patients. In this study, we sought to augment the antitumor ac...

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Detalles Bibliográficos
Publicado en:Am J Cancer Res
Main Authors: Shi, Xiumin, Li, Min, Cui, Meizi, Niu, Chao, Xu, Jianting, Zhou, Lei, Li, Wei, Gao, Yushun, Kong, Weisheng, Cui, Jiuwei, Hu, Jifan, Jin, Haofan
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851840/
https://ncbi.nlm.nih.gov/pubmed/27152238
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