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Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen sensitivity of prostate cancer cells

We identified the molecular target by histone deacetylase (HDAC) inhibitors for exploring their potential prostate cancer (PCa) therapy. Upon HDAC inhibitors-treatment, LNCaP cell growth was suppressed, correlating with increased cellular prostatic acid phosphatase (cPAcP) expression, an authentic p...

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Detalhes bibliográficos
Main Authors: Chou, Yu-Wei, Chaturvedi, Nagendra K., Ouyang, Shougiang, Lin, Fen-Fen, Kaushik, Dharm, Wang, Jue, Kim, Isaac, Lin, Ming-Fong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232184/
https://ncbi.nlm.nih.gov/pubmed/21862211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.07.015
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