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Histone deacetylase inhibitors in castration-resistant prostate cancer: molecular mechanism of action and recent clinical trials

Historically, androgen-deprivation therapy has been the cornerstone for treatment of metastatic prostate cancer. Unfortunately, nearly majority patients with prostate cancer transition to the refractory state of castration-resistant prostate cancer (CRPC). Newer therapeutic agents are needed for tre...

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Bibliografski detalji
Izdano u:Ther Adv Urol
Glavni autori: Kaushik, Dharam, Vashistha, Vishal, Isharwal, Sudhir, Sediqe, Soud A., Lin, Ming-Fong
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647138/
https://ncbi.nlm.nih.gov/pubmed/26622323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756287215597637
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