Antidepressant Actions of Histone Deacetylase Inhibitors

Persistent symptoms of depression suggest the involvement of stable molecular adaptations in brain, which may be reflected at the level of chromatin remodeling. We find that chronic social defeat stress in mice causes a transient decrease, followed by a persistent increase, in levels of acetylated h...

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Autori principali: Covington, Herbert E., Maze, Ian, LaPlant, Quincey C., Vialou, Vincent F., Ohnishi, Yoshinori N., Berton, Olivier, Fass, Dan M., Renthal, William, Rush, Augustus J., Wu, Emma Y., Ghose, Subroto, Krishnan, Vaishnav, Russo, Scott J., Tamminga, Carol, Haggarty, Stephen J., Nestler, Eric J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775805/
https://ncbi.nlm.nih.gov/pubmed/19759294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1758-09.2009
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