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Antidepressant Action of HDAC Inhibition in the Prefrontal Cortex

Previous research has demonstrated antidepressant-like effects in rodents upon intracerebral inhibition of histone deacetylases (HDACs). Such effects have been reported for local HDAC inhibition in the nucleus accumbens, hippocampus, and amygdala. However, the effect of HDAC inhibition within the me...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Covington, Herbert E., Maze, Ian, Vialou, Vincent, Nestler, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441835/
https://ncbi.nlm.nih.gov/pubmed/25907440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.04.030
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