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Histone Deacetylases Are Required for Androgen Receptor Function in Hormone-Sensitive and Castrate-Resistant Prostate Cancer

Transcriptional activity of the androgen receptor (AR) is crucial for growth and survival of prostate cancer even upon development of resistance to androgen ablation and antiandrogen therapies. Therefore, novel therapies that can suppress AR transcriptional activity when conventional hormone therapi...

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Detalhes bibliográficos
Main Authors: Welsbie, Derek S., Xu, Jin, Chen, Yu, Borsu, Laetitia, Scher, Howard I., Rosen, Neal, Sawyers, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219545/
https://ncbi.nlm.nih.gov/pubmed/19176386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2216
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