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Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies
BACKGROUND: Vascular endothelial growth factor (VEGF) is a potent regulator of angiogenesis, and its role in cancer biology has been widely studied. Many cancer therapies target angiogenesis, with a focus being on VEGF-mediated signaling such as antibodies to VEGF. However, it is difficult to predic...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229549/ https://ncbi.nlm.nih.gov/pubmed/22104283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-193 |
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