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Effect of Tumor Microenvironment on Tumor VEGF During Anti-VEGF Treatment: Systems Biology Predictions

BACKGROUND: Vascular endothelial growth factor (VEGF) is known to be a potent promoter of angiogenesis under both physiological and pathological conditions. Given its role in regulating tumor vascularization, VEGF has been targeted in various cancer treatments, and anti-VEGF therapy has been used cl...

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Detalles Bibliográficos
Autores principales: Finley, Stacey D., Popel, Aleksander S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672077/
https://ncbi.nlm.nih.gov/pubmed/23670728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt093
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