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Predicting the Effects of Anti-angiogenic Agents Targeting Specific VEGF Isoforms
Vascular endothelial growth factor (VEGF) is a key mediator of angiogenesis, whose effect on cancer growth and development is well characterized. Alternative splicing of VEGF leads to several different isoforms, which are differentially expressed in various tumor types and have distinct functions in...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3385824/ https://ncbi.nlm.nih.gov/pubmed/22547351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9363-4 |
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