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Predicting the Effects of Anti-angiogenic Agents Targeting Specific VEGF Isoforms

Vascular endothelial growth factor (VEGF) is a key mediator of angiogenesis, whose effect on cancer growth and development is well characterized. Alternative splicing of VEGF leads to several different isoforms, which are differentially expressed in various tumor types and have distinct functions in...

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Hlavní autoři: Finley, Stacey D., Popel, Aleksander S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385824/
https://ncbi.nlm.nih.gov/pubmed/22547351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9363-4
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