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The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling

Vascular endothelial growth factor (VEGF) is a potent cytokine that binds to specific receptors on the endothelial cells lining blood vessels. The signaling cascade triggered eventually leads to the formation of new capillaries, a process called angiogenesis. Distributions of VEGF receptors and VEGF...

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Bibliographic Details
Main Authors: Stefanini, Marianne O., Wu, Florence T. H., Mac Gabhann, Feilim, Popel, Aleksander S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790341/
https://ncbi.nlm.nih.gov/pubmed/20041209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000622
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