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Dimerization of VEGF receptors and implications for signal transduction: a computational study

Vascular endothelial growth factor (VEGF) is a potent cytokine involved in the induction of neovascularization. Secreted as a cysteine-linked dimer, it has two binding sites at opposite poles through which it may bind VEGF receptors (VEGFRs), receptor tyrosine kinases found on the surface of endothe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mac Gabhann, Feilim, Popel, Aleksander S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711879/
https://ncbi.nlm.nih.gov/pubmed/17442480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2007.03.010
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