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Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies

BACKGROUND: Vascular endothelial growth factor (VEGF) is a potent regulator of angiogenesis, and its role in cancer biology has been widely studied. Many cancer therapies target angiogenesis, with a focus being on VEGF-mediated signaling such as antibodies to VEGF. However, it is difficult to predic...

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Detalhes bibliográficos
Main Authors: Finley, Stacey D, Engel-Stefanini, Marianne O, Imoukhuede, PI, Popel, Aleksander S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229549/
https://ncbi.nlm.nih.gov/pubmed/22104283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-193
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