Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure

Preferential usage of immunoglobulin (Ig) genes that encode antibodies (Abs) against various pathogens is rarely observed and the nature of their dominance is unclear in the context of stochastic recombination of Ig genes. The hypothesis that restricted usage of Ig genes predetermines the antibody s...

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Hlavní autoři: Gorny, Miroslaw K., Sampson, Jared, Li, Huiguang, Jiang, Xunqing, Totrov, Maxim, Wang, Xiao-Hong, Williams, Constance, O'Neal, Timothy, Volsky, Barbara, Li, Liuzhe, Cardozo, Timothy, Nyambi, Phillipe, Zolla-Pazner, Susan, Kong, Xiang-Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229485/
https://ncbi.nlm.nih.gov/pubmed/22164215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027780
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