Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals

The recent analysis of the first successful RV144 vaccine trial revealed that a high titer of plasma anti-V2 antibodies (Abs) correlated with a decreased risk of HIV-1 infection in vaccine recipients. To understand the mechanism of immune correlates, we studied seven anti-V2 monoclonal Abs (mAbs) de...

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Main Authors: Gorny, Miroslaw K., Pan, Ruimin, Williams, Constance, Wang, Xiao-Hong, Volsky, Barbara, O'Neal, Timothy, Spurrier, Brett, Sampson, Jared M., Li, Liuzhe, Seaman, Michael S., Kong, Xiang-Peng, Zolla-Pazner, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572902/
https://ncbi.nlm.nih.gov/pubmed/22402248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.02.003
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