Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure

Preferential usage of immunoglobulin (Ig) genes that encode antibodies (Abs) against various pathogens is rarely observed and the nature of their dominance is unclear in the context of stochastic recombination of Ig genes. The hypothesis that restricted usage of Ig genes predetermines the antibody s...

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Detalhes bibliográficos
Main Authors: Gorny, Miroslaw K., Sampson, Jared, Li, Huiguang, Jiang, Xunqing, Totrov, Maxim, Wang, Xiao-Hong, Williams, Constance, O'Neal, Timothy, Volsky, Barbara, Li, Liuzhe, Cardozo, Timothy, Nyambi, Phillipe, Zolla-Pazner, Susan, Kong, Xiang-Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229485/
https://ncbi.nlm.nih.gov/pubmed/22164215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027780
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