Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure

Preferential usage of immunoglobulin (Ig) genes that encode antibodies (Abs) against various pathogens is rarely observed and the nature of their dominance is unclear in the context of stochastic recombination of Ig genes. The hypothesis that restricted usage of Ig genes predetermines the antibody s...

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Autori principali: Gorny, Miroslaw K., Sampson, Jared, Li, Huiguang, Jiang, Xunqing, Totrov, Maxim, Wang, Xiao-Hong, Williams, Constance, O'Neal, Timothy, Volsky, Barbara, Li, Liuzhe, Cardozo, Timothy, Nyambi, Phillipe, Zolla-Pazner, Susan, Kong, Xiang-Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229485/
https://ncbi.nlm.nih.gov/pubmed/22164215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027780
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