Structural Analysis of Human and Macaque Monoclonal Antibodies 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120

The quaternary neutralizing epitope (QNE) of HIV-1 gp120 is preferentially expressed on the trimeric envelope spikes of intact HIV virions, and QNE-specific monoclonal antibodies (mAbs) potently neutralize HIV-1. Here we present the crystal structures of the Fabs of human mAb 2909 and macaque mAb 2....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Spurrier, Brett, Sampson, Jared M., Totrov, Maxim, Li, Huiguang, O'Neal, Timothy, Williams, Constance, Robinson, James, Gorny, Miroslaw K., Zolla-Pazner, Susan, Kong, Xiang-Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096878/
https://ncbi.nlm.nih.gov/pubmed/21565703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.02.012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados