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Thermodynamic Signatures of the Antigen Binding Site of mAb 447–52D Targeting the Third Variable Region of HIV-1 gp120
The third variable region (V3) of HIV-1 gp120 plays a key role in viral entry into host cells; thus, it is a potential target for vaccine design. Human monoclonal antibody (mAb) 447–52D is one of the most broadly and potently neutralizing anti-V3 mAbs. We further characterized the 447–52D epitope by...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119751/ https://ncbi.nlm.nih.gov/pubmed/23944979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400645e |
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